My Lexus '06 GS300 came with run-flat tires, they hold the road well
and the tire pressure sensors work well too, having detected a 5 psi
difference between one tire and the others.  However, they are
expensive, apparently don't last as long as regular tires, and give a
harsh ride.  For this reason, when the time comes, I would like to
consider replacing them with regular tires.  If I go to my Lexus
dealer, he'll try to talk me out of it, I know, and if I go to an
independent tire dealer, I am not sure they will care whether I get the
right tire for the car or not, nor will they give a hoot about my tire
pressure sensors that must be recalibrated after each tire change.  Any
ideas out there?