This car spent its entire life on the highway; a very good sign.  If it
has had the waterpump replaced along with manufacturer's required fluid
changes, it could go another 147,000 miles with various parts replaced
along the way.  This is a 2.4 liter engine that has a timing chain
rather than a fabric belt, which is good for lower maintenance, but
they may have skipped the pump replacement which is expensive (normally
on Honda you do fabric belt & pump replacement at about 100,000 miles
as part of the maintenance).

I'd get the engine compression checked to see if they changed the oil
regularly or the rings could be shot.  (First take the oil cap off the
engine while running and see if blow-by wants to rush out of the
crankcase; excessive blowby indicates the rings are going.  Also look
at the inside of the cap and down into the engine for sludge buildup
(not changing oil) or jelly-like gunk (coolant leaking into the engine
due to gasket failure)  Check the transmission fluid if it is an
automatic; if it is dark and smells burned instead of a nice pink with
an oily smell, that would signal a problem.  These are simple checks
that can tell you a lot for free before you bother to hire a mechanic's
expertise.)  Look for paint mismatch or areas around body fasteners
under the hood or trunk that show removal -- signs the car's been
wrecked.  Check the doors, body panels and tire wear for alignment
problems, again the car could have been wrecked if these show up.

The problem is, the car is still not very old and you still won't get a
really huge, huge discount for all the miles.  Personally, I'd shoot
for a 4 or 5 year old honda.  It is financially a wiser choice.  The
2005 has seen a lot of use, and it will not be more reliable than a
2000 model with similar mileage, but will be much more expensive.
Depends on how much you love the look of the newer generation.