You're doing the right thing by asking; that's pretty heavy duty for a
car it's age.

Keep looking for input about reliability, but if you maintain it well
I'd say go ahead. A good mechanic -- if you know someone who isn't just
going to rack up the charges -- should test drive the car to catch the
noises, etc. that you don't pay attention to cause you drive it every
day.

And you might have a back up plan.

HTH

If you have regularly maintained it, then you will be fine. What you
may want to do though, just to get that extra bit of freshness and
reliability out of your system is;

Change the coolant AND repalce the hoses and thermostat. The southwest
desert, Florida and AC running continuously are going to push your
car's coolant system like never before. Check your water pump as well.
Make sure there are no leaks.

Change the tranny fluid. DO NOT do a tranny flush. Just drop the
fluid, measure how much you dropped, then replace with fresh Dexron
III fluid. It's just like changing the oil without the filter.

Oil and filter change if needed.

That's about it, really. You should be good after that.

CD

Have the car experienced any engine misfire or temporary stumble on
acceleration? If so, take off the distributor cap and underneath there is
a plastic cover held by 2 philips head screws. Under that cover there is a
shiny metallic disk with lost of small holes. gently wipe that with a
tissue paper. If you got oil on the tissue, the distributor seal that
isolate the camshaft to the distributor is failing. The engine will stop
running when there is enough oil mograting that way. This is a common
priblem with Sentra and Altimas around that mileage (happened to my 1999
Sentra with 1.6L engine). I replaced mine using a new distributor from
eBay for around $150.

160,000 miles is not much for a well maintained 1.6 Sentra.  The key
is how well maintained.  Doing the cooling system, as suggested, is a
very good idea.  Change the drive belts while you're in there too.
The water pump is a concern at that mileage if it has never been
changed.  My 1987 E16 Sentra still runs well at 333,000.  The water
pump has been changed twice, each time it went about 125,000 miles.
Good luck.  Enjoy the ride!  Al