Sure, you either hook up a clutch switch or connect to a tach signal and the cruise control detects the engine RPM change when
you shift gears.  I put one in my VW diesel pickup with 5-speed:
    http://4crawler.cruiserpages.com/Diesel/CheapTricks/CruiseControl.shtml

I had an Audiovox unit on mine.  I had to set the unit to "8 cylinder"
because it would not cruise with the RPM above 2800, meaning a 65mph
cruise was tops.

I really only had two complaints.... it obviously cannot shift for
you, so if the road is anything but flat, maintaining 70+ required
disengaging the cruise and downshifting.
The other thing I didn't like was that, since there is no clutch pedal
sensor, the unit sensed clutch release via engine RPM... any sudden
increase (or decrease, such as in an accident) resulted in the unit
shutting off.... the problem is, tapping the clutch resulted in a
VROOOOM before release.  I would always hit the "off" button on the
unit's control box before tapping the clutch... either that or tap the
brakes, but tapping the brakes was generally the last thing I wanted
to do if I was preparing to downshift to climb a hill :)

 --- Rich
 http://richlockyer.tripod.com/

Yes, but make sure you install the kill swtich ont eh cluthc pedal. I
woulndt do it anyway.

Yes you can
www.bought4less.com
has the FINEST aftermarket cruise available.
ALL parts included and Detailed instructions and Installers notes.

Price? About $140

That's less than jcwhitney

And its NOT that cheap crappy and unsafe audivox unit.