Similar results from my 2001 RX 300. Oil and filter every 5k. Always Premium
gas. Averaged 22.5 mpg in Texas with 50% hwy miles. Michelins - always! No
major problems. Oxygen sensor went at 75k, cost $350 or so. Had the timing
belt replaced at 100k as preventative measure. Sold it at 125k. Bought a
2007 RX350.

IMHO the only design flaw in that model was the turning radius Aircraft
carriers have a slightly better turning radius. I can now do a 180 in only
three lane widths!

I've had good luck with my 2001 RX. Bought it October 2000, it has 135K
miles now. Mostly highway driving. Dealer-serviced every 7500 miles.
Got over 80k miles on original Goodyears (they were just OK for cornering &
traction in snow) then put on Michelins (LTX I think) which are great.
I'm still on 2nd set of brakes front and rear, original exhaust now has a
leak which will be fixed with just a gasket.
Just about every exterior light bulb has been replaced.

Had an engine seal leak at maybe 110k miles, costly (labor, not parts) to
replace.

Winter gas mileage is about 19.5 MPG, summer is a hair over 21 using 87
octane.
No transmission trouble at all.

Been reading this group for a while, realize my experience hasn't been
shared by everyone. But mine's been great and I want it to run forever.
hth,
Bob

I'm looking at getting my wife a 2000 - 2001 RX.  What are some things to
look for?  Are the transmissions as bad as some message boards make them out
to be?